Primary research articles and preprints

Grimes K, Beckwith EJ, Pearson WH, Jacobson J, Chaudhari S, Aughey GN, Larrouy-Maumus G, Southall TD, Dionne MS. A serine-folate metabolic unit controls resistance and tolerance of infection. bioRxiv 2022.11.25.517956.

Wadhawan A, Simoes da Silva CJ, Nunes CD, Edwards AM, Dionne MS. E. faecalis acquires resistance to antimicrobials and insect immunity via common mechanisms. bioRxiv 2022.08.17.504265.

Vincent CM, Beckwith EJ, Simoes da Silva CJ, Pearson WH, Kierdorf K, Gilestro G, Dionne MS. Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster. PLOS Pathogens 18: e1010826.

Tonkin RL, Klöckner A, Najer A, Simoes da Silva CJ, Echalier C, Dionne MS, Edwards AM, Stevens MM (2022). Bacterial toxin-triggered release of antibiotics from capsosomes protects a fly model from lethal methicillin-resistant Staphylococcus aureus (MRSA) infection. Advanced Healthcare Materials 28: e2200036.

Boeck L, Burbaud S, Skwark M, Pearson WH, Sangen J, Weimann A, Everall I, Bryant JM, Malhotra S, Bannerman BP, Kierdorf K, Blundell TL, Dionne MS, Parkhill J, Floto RA (2022). The pathobiology of Mycobacterium abscessus revealed through phenogenomic analysis. Nature Microbiology 7: 1431-1441.

Rose S, Beckwith EJ, Burmester C, May RC, Dionne MS, Rezaval C (2022). Pre-copulatory reproductive behaviours are preserved in Drosophila melanogaster infected with bacteria. Proceedings of the Royal Society B: Biological Sciences 289: 20220492.

Janssens J, Aibar S, Taskiran II, Ismail JN, Gomez AE, Aughey G, Spanier KI, De Rop FV, González-Blas CB, Dionne M, Grimes K, Quan XJ, Papasokrati D, Hulselmans G, Makhzami S, De Waegeneer M, Christiaens V, Southall T, Aerts S. (2022) Decoding gene regulation in the fly brain. Nature 601: 630-636.

Vincent CM, Dionne MS. (2021) Disparate regulation of imd drives sex differences in infection tolerance in Drosophila melanogaster. Proceedings of the National Academy of Sciences USA 118: e2026554118.

Klionsky DJ, and 4000 others, including Dionne MS. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 17: 1-382.

Rismondo J, Schulz LM, Yacoub M, Wadhawan A, Hoppert M, Dionne MS, Gründling A. (2021) EslB is required for cell wall biosynthesis and modification in Listeria monocytogenes. J Bacteriol 203: e00553-20.

Vincent C, Simoes da Silva CJ, Wadhawan A, Dionne MS. (2020) Origins of metabolic pathology in Francisella-infected Drosophila. Frontiers in Immunology 11:1419.

Kierdorf K, Hersperger F, Sharrock J, Vincent CM, Ustaoglu P, Dou J, Gyoergy A, Groß O, Siekhaus DE, Dionne MS. (2020) Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila. eLife 9: e51595.

Sharrock J, Estacio-Gomez A, Jacobson J, Kierdorf K, Southall TD, Dionne MS. (2019) fs(1)h controls metabolic and immune function and enhances survival via AKT and FOXO in Drosophila. Disease Models and Mechanisms 12: dmm037259.

Gordon O, Henry CM, Srinivasan N, Ahrens S, Franz A, Deddouche S, Chakravarty P, Philips D, George R, Kjaer S, Frith D, Snijders AP, Valente RS, Simoes da Silva CJ, Teixeira L, Thompson B, Dionne MS, Wood W, Reis E Sousa C. (2018) α-actinin accounts for the bioactivity of actin preparations in inducing STAT target genes in Drosophila melanogaster. eLife 7: e38636.

Péan CB, Schiebler M, Tan SWS, Brown KP, Maserumule MC, Menezes S, Pilátová M, Bronda K, Guermonprez P, Stramer BM, Floto RA, Dionne MS. (2017) Regulation of phagocyte triglyceride by a STAT-ATG2 pathway controls mycobacterial infection. Nature Communications 8: 14642.

Srinivasan N, Gordon O, Ahrens S, Franz A, Deddouche S, Chakravarty P, Philips D, Yunus AA, Rosen MK, Valente RS, Teixeira L, Thompson B, Dionne MS, Wood W, Reis E Sousa C. (2016) Actin is an evolutionarily-conserved damage-associated molecular pattern that signals tissue injury in Drosophila melanogaster. eLife 5: e19662.

Cagin U, Duncan OF, Gatt AP, Dionne MS, Sweeney ST, Bateman JM. (2015) Mitochondrial retrograde signaling regulates neuronal function. Proc Natl Acad Sci U S A 112: E6000-E6009.

Woodcock KJ, Kierdorf K, Pouchelon CA, Vivancos V, Dionne MS, Geissmann F. (2015) Macrophage-derived upd3 cytokine causes impaired glucose homeostasis and reduced lifespan in Drosophila fed a lipid-rich diet. Immunity 42: 133-144.

Colas C, Menezes S, Gutiérrez-Martínez E, Péan CB, Dionne MS, Guermonprez P. (2014) An improved flow cytometry assay to monitor phagosome acidification. Journal of Immunological Methods 412: 1-13.

Clark RI, Tan SWS, Péan CB, Roostalu U, Vivancos V, Bronda K, Pilátová M, Fu J, Walker DW, Berdeaux R, Geissmann F, Dionne MS. (2013) MEF2 is an in vivo immune-metabolic switch. Cell 155: 435-447.

Pilátová M, Dionne MS. (2012) Burkholderia thailandensis is virulent in Drosophila melanogaster. PLoS One 7: e49745.

Clark RI, Woodcock KJ, Geissmann F, Trouillet C, Dionne MS. (2011) Multiple TGF-β superfamily signals modulate the adult Drosophila immune response. Current Biology 21: 1672-1677.

Shirasu-Hiza M, Dionne MS, Pham LN, Ayres JS, Schneider DS. (2007) Interactions between circadian rhythm and immunity in Drosophila melanogaster. Current Biology 17: R353-R355.

Schneider DS, Ayres JS, Brandt SB, Costa A, Dionne MS, Gordon MD, Mabery EM, Moule MG, Pham LN, Shirasu-Hiza M. (2007) Drosophila eiger mutants are sensitive to extracellular pathogens. PLoS Pathogens 3: e41.

Pham LN, Dionne MS, Shirasu-Hiza M, Schneider DS. (2007) A specific primed immune response in Drosophila is dependent on phagocytes. PLoS Pathogens 3: e26.

Dionne MS, Pham LN, Shirasu-Hiza M, Schneider DS. (2006) Akt and foxo dysregulation contribute to infection-induced wasting in Drosophila. Current Biology 16: 1977-1985.

Gordon MD, Dionne MS, Schneider DS, Nusse R. (2005) WntD is a feedback inhibitor of Dorsal/NF-κB in Drosophila development and immunity. Nature 437: 746-749.

Brandt SB, Dionne MS, Khush RS, Pham LN, Vigdal TJ, Schneider DS. (2004) Secreted bacterial effectors and host produced eiger/TNF drive death in a Salmonella-infected fruit fly. PLoS Biology 2: e418.

Mansfield BE, Dionne MS, Schneider DS, Freitag NE. (2003) Exploration of host-pathogen interactions using Listeria monocytogenes and Drosophila melanogaster. Cellular Microbiology 5: 901-911.

Khokha MK, Hsu D, Brunet LJ, Dionne MS, Harland RM. (2003) Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning. Nature Genetics 34: 303-307.

Dionne MS, Ghori N, Schneider DS. (2003) Drosophila melanogaster is a genetically-tractable model host for Mycobacterium marinum. Infection and Immunity 71: 3540-3550.

Dionne MS, Brunet LJ, Eimon PM, Harland RM. (2002) Noggin is required for correct guidance of dorsal root ganglion axons. Developmental Biology 251: 283-293.

Dionne MS, Skarnes WC, Harland RM. (2001) Mutation and analysis of Dan, the founding member of the Dan family of Transforming Growth Factor β antagonists. Molecular and Cellular Biology 21: 636-643.

Gibney G, Camp S, Dionne M, MacPhee-Quigley K, Taylor P. (1990) Mutagenesis of essential functional residues in acetylcholinesterase. Proc Natl Acad Sci U S A 87: 7546-7550.

Reviews

Marshall EKP, Dionne MS (2021) Drosophila versus Mycobacteria: A model for mycobacterial host-pathogen interactions. Mol Microbiol 2021 Sep 29.

Feng Y, Dionne MS, Stamatiades EG, Kierdorf K. (2021) Editorial: Deciphering phagocyte function across different species. Front Cell Dev Biol 9: 712929.

Kierdorf K, Dionne MS. (2016) The software and hardware of macrophages: a diversity of options. Developmental Cell 38: 122-125.

Stramer BM, Dionne MS. (2014) Unraveling tissue repair immune responses in flies. Seminars in Immunology 26: 310-314.

Dionne MS. (2014) Immune-metabolic interaction in Drosophila. Fly 8: 2.

Clark RI, Walker DW, Dionne MS. (2014) Metabolic and immune integration in aging and age-related disease. Aging 6: 3-4.

Péan CB, Dionne MS. (2014) Intracellular infections in Drosophila melanogaster: host defense and mechanisms of pathogenesis. Developmental and Comparative Immunology 42: 57-66.

Dionne MS. (2013) Comparative immunology: allorecognition and variable surface receptors outside the jawed vertebrates. Current Opinion in Immunology 25: 608-612.

Dionne MS, Schneider DS. (2008) Models of infectious diseases in the fruitfly Drosophila melanogaster. Disease Models and Mechanisms 1: 43-49.

Dionne MS, Schneider DS. (2002) Screening the fruitfly immune system. Genome Biology 3: REVIEWS1010.